• Le 13 December 2022
    Amphi 5, Faculté de Médecine, Bâtiment Veil, 1er étage
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  • Mardi 13 décembre 2022 à 11H,

Dr Thomas SIMON, IPMC - Institut de Pharmacologie Moléculaire et Cellulaire, UMR7275 CNRS/UCA - VALBONNE Treatment of autoimmune diseases by neuromodulation”. Invité par le Dr Ignacio Anegon

Thomas Simon did a PhD in Immunology at the CRCI-NA, Nantes, from 2005 to 2008, under the supervision of Marc Gregoire, working on anti-tumoral immunotherapies.

In 2009, he joined Ignacio Anegon’ lab at the CR2TI, Nantes and worked on the role of heme oxygenase-1 in the induction of tolerance for autoimmune diseases.

In 2014, he moved to Baltimore as post-doctoral fellow and joined Prof. Jonathan Bromberg at University of Maryland School of Medicine. Over three years, his work focused on immune cell trafficking, secondary lymphoid organ structure and function and how these processes and structures influence T cell immunity and T cell tolerance in models of cardiac transplantation.

Upon his return to France in 2017 at the Molecular and Cellular Pharmacology Institute (CNRS-UNS) in Nice, he has refocused his research to investigate how the peripheral nervous and the immune systems interact in the context of autoimmunity. He started to work on the potential use of bioelectronics as therapy to treat Immuno-Mediated Inflammatory Diseases, and more specifically autoimmune diabetes and inflammatory arthritis. The aim of his research is to identify clinically relevant point of intervention in human and to characterize the potential beneficial effects of electrical stimulation of peripheral nerves for inflammatory diseases. In 2019, he was appointed Associate Professor of immunology at the Université Côte d’Azur and co-lead a research team at the Molecular and Cellular Pharmacology Institute (CNRS-UNS).