Center for Research in Transplantation and Translational Immunology

Discover our teams and core facilities

Mononuclear phagocytes, Immunopathology, Immunovirology (Team 1) Cell and gene engineering in tolerance, fertility and regenerative medicine (Team 2) Integrative transplantation, HLA, Immunology and genomics of kidney injury (Team 3) Deciphering organ immune regulation in inflammation and transplantation: DORI-t (Team 4) Neuroinflammation, mechanisms, therapeutic options : NEMO (Team 5) Impact of acute inflammation on host-pathogen interactions and lung homeostasis (Team 6) Equipments & Core Facilities Support

Selected publications

  • Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis. Nat Immunol. PMID 32424365
  • Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis. J Hepatol. PMID 32649971
  • Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification. Cell Stem Cell. PMID 34004179
  • Selective SIRPa blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance. J Clin Invest. PMID 33074246
  • Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution. Sci Adv PMID 33811066

Events calendar

Progreffe - Make a donation

You too can help advance research in organ transplantation and immunology. Make a donation to Progreffe Fondation that will be used to fund the work of researchers at the CR2TI and the ITUN at the University Hospital of Nantes. Donate

News

CR2TI at the SFT and SFI meetings

CR2TI awarded by Nantes Innovation Campus

CR2TI teams involved in the RHU Primus Project

Latest thesis defense

Many doctoral students have defended their thesis in the last few weeks

BioMAdvanced Diagnostics : a new spin-off !

BioMAdvanced Diagnostics created by Dr S brouard and Dr R Danger, a new spinn off from the CR2TI

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